University of California San Francisco

Dr. Warren Gasper
Warren
Gasper
MD

Associate Professor of Surgery,
Division of Vascular and Endovascular Surgery
Department of Surgery, School of Medicine
Chief, Vascular Surgery Section,
San Francisco VA Health Care System
Director, Vascular Integrated Physiology and
Experimental Therapeutics (ViperX)
Associate Director, Vascular Surgery Integrated Residency Program

Academic Office:
400 Parnassus Ave, A581, Box 0222
San Francisco, CA 94143
Tel: 415-353-4366
Email: Warren.Gasper@ucsf.edu 
Asst: Matt.Kuhn@ucsf.edu

Vascular Surgery Clinic:
400 Parnassus Ave, A501, Box 0957
San Francisco, CA 94143
Tel: 415-353-2357
Fax: 415-353-2669

Vascular Surgery Clinic at SFVA:
4150 Clement Street 
San Francisco, CA 94121
Tel: 415-221-4810 x25496 

Biography

My current research interests fall broadly into the categories of vein / vein graft physiology and advanced endovascular aneurysm therapies. Over the past 4 years I have been working with Dr Michael Conte and Dr Christopher Owens in the UCSF Division of Vascular and Endovascular Surgery on several projects involving vein graft physiology, which have lead to several presentations at national meetings as well as publications. We have found that after lower extremity bypass surgery most luminal dilation occurs early (30 days) and is typically complete by 3 months. However, the response is not uniform and it appears that a mixture of local factors (e.g. vein diameter and quality), biologic factors (e.g. preoperative hsCRP levels) and systemic factors (e.g. race, indication for bypass surgery) are involved in the remodeling response.
My second major area of research interest is advanced endovascular therapies for aortic aneurysms. The development and widespread adoption of endovascular stent-grafts for infrarenal aortic aneurysms and thoracic aortic aneurysms have dramatically reduced the physiologic demands, complication rates and length of hospitalization for patients undergoing infrarenal or thoracic aortic aneurysm repairs compared to open techniques. However, aneurysms of thoracoabdominal, paravisceral and/or pararenal aorta require even more demanding operations with a higher rate of complications and longer hospitalizations. For the past 4 years I have worked with Dr. Timothy Chuter and Dr. Linda Reilly in the UCSF Division of Vascular and Endovascular Surgery to develop the multi-branched endovascular thoracoabdominal aneurysm repair technique. The technique is being studied under an FDA IDE in a CHR-approved study at UCSF and the San Francisco VA. As the co-principal investigator, I am responsible for overseeing the regulatory and subject care activities for the study at the San Francisco VA. This work has included consultations in the outpatient clinic, planning and performing the multi-branched endovascular repairs and analyzing the results of the study.

Education

Institution Degree Dept or School End Date
University of California, San Francisco Vascular Surgeyr Fellowship School of Medicine 2013
University of California, San Francisco Vascular Surgery Fellowship School of Medicine 2011
University of California, San Francisco General Surgery Residency School of Medicine 2010
Univeristy of Maryland, Baltimore M.D. School of Medicine 2003
Bowdoin College A.B Biochemistry & German 1999

Awards & Honors

Award Conferred By Date
Lim/Thomas Excellence in Teaching Award UCSF Department of Surgery Chief Residents 2018
Excellence in Teaching Award UCSF Haile T. Debas Academy of Medical Educators 2017
First place, Poster Competition Society for Vascular Surgery Annual Meeting 2011

Clinical Expertise

Aortic Dissection

Abdominal Aortic Aneurysm

Carotid Artery Disease

Complex Limb Revascularization

Critical Limb Ischemia

Diabetic Vascular Disease

Dialysis Access

Endovascular Aneurysm Repair

Mesenteric Artery Disease

Peripheral Artery Disease

Thoracic Aortic Aneurysm

Thoracic Outlet Syndrome

Clinical Trials

  1. Related Conditions: Aneurysm, Abdominal Aortic Aneurysm| Start Date: | End Date:
  2. Related Conditions: Aneurysm| Start Date: | End Date:
  3. Related Conditions: Peripheral Artery Disease, Vascular Disease, Chronic Limb-Threatening Ischemia, Critical Limb Ischemia, MRI, Neuroimaging| Start Date: | End Date:
  4. Related Conditions: Peripheral Artery Disease, Vascular Disease| Start Date: | End Date:
  5. Related Conditions: Peripheral Artery Disease, Abdominal Aortic Aneurysm, Aneurysm| Start Date: | End Date:
  6. Related Conditions: Peripheral Artery Disease, Vascular Disease| Start Date: | End Date:
  7. Related Conditions: Peripheral Artery Disease, Vascular Disease| Start Date: | End Date:
  8. Related Conditions: Peripheral Artery Disease, Vascular Disease| Start Date: | End Date:
  9. Related Conditions: Peripheral Artery Disease, Cardiovascular Disease, Vascular Disease| Start Date: | End Date:
  10. Related Conditions: Chronic Kidney Disease, Kidney Disease, Arteriovenous Fistula, Fistula| Start Date: | End Date:

In the News

November, 09, 2022 | UCSF Division of Vascular & Endovascular Surgery
August, 12, 2011 | UCSF Vascular & Endovascular Surgery

Grants and Funding

  • Transfusion Trigger after Operations in High Cardiac Risk Patients | VA Cooperative Studies Program | 2017-10-01 - 2022-02-28 | Role: Co-local Site Investigator
  • Targeted Endovascular Treatment of Inflammation for Vascular Healing in Humans | NIH/NHLBI | 2015-08-18 - 2020-04-30 | Role: Co-Investigator
  • Imaging Substudy, part of "A Phase 2 Study for the Evaluation of Safety and Efficacy of Humacyte's Human Acellular Vessel for Use as a Vascular Prosthesis for Femoro-Popliteal Bypass in Patients With Peripheral Arterial Disease" | Industry | 2016-06-13 - 2020-03-31 | Role: Principal Investigator
  • Randomized, Multicenter, Controlled Trial to Compare Best Endovascular versus Best Surgical Therapy in Patients With Critical Limb Ischemia (BEST-CLI) | NIH/NHLBI | 2014-12-01 - 2019-12-31 | Role: Principal Investigator

Research Narrative

Dr. Gasper’s clinical interests include diseases of the aorta and its major branches, aneurysms and peripheral artery disease. Dr Gasper’s research has been focused on translational projects involving vascular physiology and venous remodeling after arteriovenous fistula and lower extremity bypass surgeries. He also been active in research involving pharmacologic therapies to reduce or prevent restenosis and has been involved in pre-clinical studies as well as clinical trials using a novel endovascular approach to deliver therapy to the artery adventitia.

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 115
  1. Outcomes using inverted iliac limb bifurcate components in fenestrated/branched endografting.
    Khoury MK, Beck AW, Farber MA, Gasper W, Lee WA, Oderich G, Parodi FE, Schanzer A, Schneider D, Sweet M, Timaran CH, Eagleton MJ| | PubMed
  2. Early Opioid Use and Postoperative Delirium Following Open Abdominal Aortic Aneurysm Repair.
    Gutierrez RD, Pepic L, Lancaster EM, Gasper WJ, Hiramoto JS, Conte MS, Bongiovanni T, Iannuzzi JC| | PubMed
  3. Early and Late Aortic-Related Mortality and Rupture After Fenestrated-Branched Endovascular Aortic Repair of Thoracoabdominal Aortic Aneurysms: A Prospective Multicenter Cohort Study.
    Oderich GS, Huang Y, Harmsen WS, Tenorio ER, Schanzer A, Timaran CH, Schneider DB, Mendes BC, Eagleton MJ, Farber MA, Gasper WJ, Beck AW, Sweet MP, Lee WA, United States Aortic Research Consortium| | PubMed
  4. Postdissection aortic aneurysm sac enlargement after fenestrated and branched endovascular aortic aneurysm repair.
    Figueroa AV, Tanenbaum MT, Timaran CH, Oderich GS, Eagleton MJ, Schanzer A, Farber MA, Beck AW, Schneider DB, Gasper W, Sweet MP, Lee A, Cantor RS, Li X| | PubMed
  5. Practice patterns of antiplatelet and anticoagulant therapy after fenestrated/branched endovascular aortic repair.
    Fan EY, Schanzer A, Beck AW, Eagleton MJ, Farber MA, Gasper WJ, Lee WA, Oderich GS, Parodi FE, Schneider DB, Sweet MP, Timaran CH, Simons JP, US Aortic Research Consortium| | PubMed
  6. Preoperative risk factors for 1-year mortality in patients undergoing fenestrated endovascular aortic aneurysm repair in the US Aortic Research Consortium.
    Banks CA, Novak Z, Spangler EL, Schanzer A, Farber MA, Sweet MP, Oderich G, Timaran CH, Lee A, Schneider DB, Eagleton MJ, Gasper W, Beck AW| | PubMed
  7. Prospective randomized pilot trial comparing prophylactic and therapeutic cerebrospinal fluid drainage during complex endovascular thoracoabdominal aortic aneurysm repair.
    Blakeslee-Carter J, Novak Z, Jansen JO, Schanzer A, Eagleton MJ, Farber MA, Gasper W, Lee WA, Oderich GS, Timaran CH, Schneider DB, Sweet MP, Beck AW| | PubMed
  8. Relevance of BEST-CLI trial endpoints in a tertiary care limb preservation program.
    Liu IH, El Khoury R, Hiramoto JS, Gasper WJ, Schneider PA, Vartanian SM, Conte MS| | PubMed
  9. Secondary interventions following open vs endovascular revascularization for chronic limb threatening ischemia in the BEST-CLI trial.
    Conte MS, Azene E, Doros G, Gasper WJ, Hamza T, Kashyap VS, Guzman R, Mena-Hurtado C, Menard MT, Rosenfield K, Rowe VL, Strong M, Farber A| | PubMed
  10. Predictors of amputation-free survival and wound healing after infrainguinal bypass with alternative conduits.
    Matthay ZA, Pace WA, Smith EJ, Gutierrez RD, Gasper WJ, Hiramoto JS, Reilly LM, Conte MS, Iannuzzi JC| | PubMed